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KMID : 0352819920080010063
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Kosin Medical Journal
1992 Volume.8 No. 1 p.63 ~ p.70
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the Effect of Mothers' Hepatitis B Virus Markers on the positive Rates of Anti-HBc
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Abstract
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In order to study the positive rates of Anti-HBc and Anti-HBs in infants after the completion of veccination in relation to their mothers' hepatitis B virus(HBV) markers 149 infants were selected in whom the HBsAg, Anti-HBc, and
Anti-HBs
were tested 2-3 months after completion of vaccination. Their mother's HBV markers had been examined in the second half of pregnancy and the infants were classifieds in to four groups according to the nature of their mother's HBV markers.
Group A, 18 infants whose mothers were HBsAg(+), Anti-HBc(+), and HBeAg(+)
Group B, 24 infants whose mothers were HBsAg(+), Anti-HBc(+), and HBeAg(-)
Group C, 71 infants whose mothers were only Anti-HBc(+)
Group D, 36 infants whose mothers were GBsAg(-), Anti-HBc(-) and AntiHBs(-)
when the positive rates of the infants were compared, The results were as follows:
1. The positive rates of anti-HBc in groups A and B, in both of which the mothers were HBsAg(+) and anti-HBc(+), were statistically significantly higher than those of Group c in which the mothers were only Anti-HBc(+).
2. There was no statistically significant relationship between the nature of the mothers' HBV markers and positive rates of AntiHBs in the infants.
3. There was no significant relationship between the positive rates of Anti-HBc and Anti-HBs in infants and the status of HBeAg in their carrier mothers.
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